Searchable abstracts of presentations at key conferences in endocrinology

ea0008p23 | Cytokines and growth factors | SFE2004

Variability in IGF-I assay performance undermines its contribution to the management of GH axis disorders

Pokrajac-Simeunovic A , Wark G , Wieringa GE , Trainer PJ

IGF-I is a marker of activity of the growth axis. It is accepted that the interpretation of IGF-I values requires age- and gender-specific reference ranges (RR).We have studied IGF-I assay performance by circulating 2 blood samples with different clinical scenarios to 23 centers [IDS-OCTEIA (n=2), DPC-Immulite (3), DPC-Immulite 2000 (4), in-house RIA (1), Nichols-Advantage (10) and Nichols-IRMA (3)] participating in the UK-NEQAS IGF-I scheme. Participant...